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Europe’s largest plasma products company: Grifols, SA (GRFS) (1940)

Grifols, SA (NASDAQ: GRFS) was founded in 1940 and is headquartered in Barcelona, ​​Spain. It has 14,749 full-time employees. It is a biopharmaceutical company that develops, manufactures and manufactures products in the United States, Canada, Spain, other EU countries and internationally. It sells plasma-derived products and mainly manufactures serum-related products such as human albumin. It is the largest plasma product company in Europe and the fourth largest in the world.

Grifols 1

Grifols, SA (GRFS):

Grifols, SA is a Spanish multinational pharmaceutical and chemical company. The company is mainly a plasma product manufacturer and a leading plasma product manufacturer in Europe and the world. In addition, Grifols also provides equipment, instruments and reagents for clinical testing laboratories .

Grifols specializes in providing infusion solutions, nutritional products, medical equipment, diagnostic instruments and reagents used in hospitals and clinics. The company is divided into 4 departments to operate:

1. Bioscience-manufacture of plasma derivatives for therapeutic purposes, including the reception, analysis, quarantine, classification, fractionation and purification of plasma; and sale and distribution of final products. Provide plasma products, including IVIG, Factor VIII, A1PI and albumin; intramuscular immunoglobulin, ATIII, Factor IX and plasma thromboplastin components.

2. Diagnostic (Diagnostic)-committed to the research, development, manufacturing and sales of in vitro diagnostic products, including analytical instruments, reagents, software and related products for clinical and blood bank laboratories. This department serves blood donation centers, clinical analysis laboratories, and hospital immunohematology.

3. Hospital-manufacture and install products used in hospitals, such as parenteral solutions, enteral and parenteral fluid systems.

4, raw materials and other (Raw Materials and Others) – intermediate sale of biological products; and to provide third-party manufacturing services company.

Gilifu also provides engineering services. Its products and services are used by healthcare providers to diagnose and treat patients with hemophilia, immunodeficiency, infectious diseases and other medical conditions. The company provides services to hospitals and clinics, group purchasing organizations, governments and other distributors through sales representatives, marketing partners and third-party distributors.

Grifols, SA (GRFS) product encyclopedia (same product name, only translated once) :

1. The United States

HyperRHO® S/D (Rho (D) immunoglobulin (human)), Flebogamma® 5% DIFImmune Globulin Intravenous (Human), 5% (human immunoglobulin for intravenous injection), GAMUNEX®-Cimmune globulin injection (human), 10% (human immunoglobulin for injection, 10% caprylic acid/chromatographic purification), DOSI-FUSER® (disposable, continuous infusion system), PROLASTIN®-Calpha1-proteinase inhibitor (human) (α1-human protease inhibitor), Misterium® (modular clean room solutions and operational consulting services), Phocus Rx® (workflow management system), Flebogamma® 10% DIFImmune Globulin Intravenous (Human), 10% (human immunoglobulin intravenous injection, 10%), AlphaNine® S/D (coagulation factor IX [human]), ALPHANATE® (human antihemophilia factor/von Willebrand factor complex), PROFILNINE® (factor IX complex) (factor IX complex) Complex), Thrombate III®Antithrombin III (Human), KIRO® Oncology (a new generation of robots for aseptic preparation of dangerous drugs), Gri-fill® 3.0, Plasbumin®-25 (Low Aluminum )Albumin (Human) 25%, USP (Human Albumin), Plasbumin®-5 (Low Aluminum)Albumin (Human) 5%, USP, Wadiana® (Compact Automatic Blood Bank System), Albumin® 25% (Human Albumin) ), GamaSTAN® S/DImmune Globulin (Human), Albutein® 5%Albumin (Human), 5% USP(Human albumin), Plasmanate®Plasma Protein Fraction (Human) 5%, USP (human plasma protein), HyperHEP® BS/DHepatitis B Immune Globulin (Human), HyperRAB® S/DRabies Immune Globulin (Human) (Human Rabies Immune Globulin), HyperTET® S/DTetanus Immune Globulin (Human) (Tetanus Immune Globulin)

2. Asia Pacific (Southeast Asia)

1. China: Human Albumin Grifols® 20% (Grifols® human albumin 20%), KIRO® Oncology (the next generation of robots used for aseptic preparation of dangerous drugs)-Grifols has only 2 products in China. If you want to buy their products, it is recommended to go to the nearest Japan, Singapore, or the United States, Spain (the most complete, more than 110 products on sale).

2. Japan : KIRO® Oncology, BlisPack® (automatic identification, cutting and packaging of blister tablets), BLUE® (Blood Unit Expert)

3. Australia : Flebogamma® 5% DIF 50 mg/ml, Flebogamma® 10% DIF 100 mg/ml, KIRO® Oncology, BlisPack®, BLUE® (Blood Unit Expert)

4. Singapore : Flebogamma® 5% DIF / Flebogamma® DIF 50 mg/ml, Misterium®, Human Albumin Grifols® 5% (Gilifo® human albumin 5%), Anbinex®, AlphaNine® / AlphaNine® SD, Human Albumin Grifols® 20% (Gillif® human albumin 20%), Igantibe® / Gamma Anti-Hepatitis B Grifols® / Pasteurised Human Antihepatitis B Immunoglobulin Grifols®, Niuliva®, Alphanate®, Profilnine® SD, KIRO® Oncology, Gri-fill® 3.0, BlisPack®, Gamma Anti-Tétanos Grifols® / Igantet® / Pasteurised Human Antitetanus Immunoglobulin Grifols®, Igamplia® 160mg/ml / Pasteurised Human Immunoglobulin Grifols® 16% / Gammaglobulina Humana Pasteurizada Grifols® / Gammaglobulina Humana Pasteurizada Grifols® / Gammaglobulina Humana Pasteurizada Grifols® / Gammaglobulina Grifols®, Albutein® 20%, Albutein® 25%, Albutein® 5%, BLUE® (Blood Unit Expert)

5. Malaysia : Flebogamma® 5% DIF / Flebogamma® DIF 50 mg/ml, Misterium®, Albúmina Humana Grifols® 5% (Gilifo® human albumin 5%), AlphaNine® / AlphaNine® SD, Albaúmina Humana Grifols ® 20%, Fanhdi®, Igantibe® / Gamma Anti-Hepatitis B Grifols® / Pasteurised Human Antihepatitis B Immunoglobulin Grifols®, Alphanate®, Profilnine® SD, KIRO Oncology, Gri-fill® 3.0, BlisPack®, Gamma Anti-Tétanos Grifols ® / Igantet® / Pasteurised Human Antitetanus Immunoglobulin Grifols®, Albutein® 25%, Albutein® 5%, BLUE® (Blood Unit Expert)

3. Europe, Middle East and Africa

1. Czech Republic : Gamunex® 10%, KIRO® Oncology (next generation robots for aseptic preparation of dangerous drugs), Enteral Nutri-Bag®, Flebogamma® 5% DIF 50 mg/ml, Flebogamma® 10% DIF 100 mg/ ml, Fanhdi®, Human Albumin Grifols® 20%, Human Albumin Grifols® 5%, Anbinex®

2. Dubai : KIRO® Oncology (the next generation of robots used for aseptic preparation of dangerous drugs)

3. Switzerland : KIRO® Oncology, BlisPack® (automatic identification, cutting and packaging of blister tablets), BLUE® (Blood Unit Expert)

4. Spain : Flebogamma® 5% DIF 50 mg/ml, Prolastin® / Prolastina® / Pulmolast®, Misterium®, Flebogamma® 10% DIF 100 mg/ml, Anbinex®, Fanhdi®, Dietgrif® Activ Protein Diabet, Fleboflex® Luer, Igantibe® / Gamma Anti-Hepatitis B Grifols® / Pasteurised Human Antihepatitis B Immunoglobulin Grifols®, Igamad® / Igantid® / Gamma Anti-D Grifols® / Pasteurised Anti-D Immune Globulin Grifols®, Niuliva®, Sodium Chloride Grifols® 0.45%, Ringer Grifols® / Ringer Lactate Grifols®, Potassium Grifols® and about 90 other products

5. Portugal : StocKey® RFID Smart Cabinet, Gri-fill® 3.0, BlisPack®, Mic® Jejunostomy Tubes, Mic® PEG tubes, Enteral Nutri-Bag®, Dietgrif® Estándar Fibra 60/40, Dietgrif® Estándar, Dietgrif® Polipeptídico And other 30 products

6. Poland : Flebogamma® 5% DIF / Flebogamma® DIF 50 mg/ml, Flebogamma® 10% DIF / Flebogamma® DIF 100 mg/ml, Anbinex®, Human Albumin Grifols® 20%, Fanhdi®, KIRO® Oncology, BlisPack ®, Gamma Anti-Tétanos Grifols® / Igantet® / Pasteurised Human Antitetanus Immunoglobulin Grifols®, BLUE® (Blood Unit Expert)

7. Sweden : Flebogamma® 5% DIF / Flebogamma® DIF 50 mg/ml, Gamunex® 10%, Prolastin® / Prolastina® / Pulmolast®, Flebogamma® 10% DIF / Flebogamma® DIF 100 mg/ml, KIRO® Oncology, BlisPack®, XEPOL® 50 mg/ml, BLUE® (Blood Unit Expert)

8. Italy : Misterium®, StocKey® RFID Smart Cabinet, KIRO® Oncology, Gri-fill® 3.0, BlisPack®, StocKey® Kanban

9. Germany : Flebogamma® DIF 50 mg/ml, Gamunex® 10%, Prolastin®, Misterium®, Flebogamma® DIF 100 mg/ml, Albutein® 50 g/l, Anbinex®, AlphaNine® / AlphaNine® SD, Albumein® 200 g/l

10. France : KIRO® Oncology, BlisPack®, BLUE® (Blood Unit Expert)

Grifols, SA (GRFS) History:

  • In 1940, José A. Grifols Roig founded the business;
  • On June 22, 1987, Probitas Pharma, SA was officially registered and established;
  • In 2003, Gilliford acquired Alpha Therapeutic (Mitsubishi Pharma Corporation, a subsidiary of Mitsubishi Pharma Corporation, a subsidiary of Mitsubishi Chemical Holdings Corporation) in Los Angeles, California;
  • On June 27, 2005, the company changed its name to Grifols, SA;
  • On May 17, 2006, Grifols IPO was listed on the Mercado Continuo stock exchange in Spain;
  • In 2009, CSL Limited (ASX: CSL) tried to acquire Talecris Biotherapeutics (Biological Products Division, Bayer HealthCare LLC’s plasma business unit) for US$3.1 billion, and was stopped by the Federal Trade Commission.
  • On June 1, 2011, Killifco completed the acquisition of Talecris Biotherapeutics, the biological products division of Bayer HealthCare LLC , for US$4 billion ;
  • In 2013, Grifols acquired Novartis ‘ blood transfusion diagnostic business;
  • In 2015, Killifco acquired 45% of Alkahest’s equity as a planned joint development of “plasma-based products for the treatment of CNS (including Alzheimer’s disease) aging and cognitive decline in disorders”;
  • On December 15, 2016, Gilliford confirmed the acquisition of Hologic (HOLX)’s shares in its joint venture. GRFS will complete the acquisition with a long-term loan of US$1.7 billion and existing book cash (a total of US$1.85 billion).
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